Molecular identification of Mycobacterium avium subspecies paratuberculosis in an Italian patient with Hashimoto’s thyroiditis and Melkersson–Rosenthal syndrome

To the best of our knowledge, this report is the first observation of a MAP infection in a patient with MRS. The findings are consistent with early exposure to dietary cows’ milk and underline the possibility that milk from cattle with Johne’s disease could be a potential transmission vehicle for MAP to humans.

~D’Amore M, Lisi S, Sisto M, Cucci L, Dow CT.
J Med Microbiol. 2010 Jan;59(Pt 1):137-9. Epub .
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Proposing a relationship between Mycobacterium avium subspecies paratuberculosis infection and Hashimoto’s thyroiditis

Humans are widely exposed to Mycobacterium avium subspecies paratuberculosis (MAP), a proven multi-host chronic enteric pathogen that has recently been linked to autoimmune diabetes. In the present study we used a MAP speciesspecific polymerase chain reaction with the insertion element IS900-specifi c probe to detect MAP infection in members of the same family suffering from Hashimoto’s thyroiditis.

~Sisto M, Cucci L, D’Amore M, Dow TC, Mitolo V, Lisi S.
Scand J Infect Dis. 2010 Oct;42(10):787-90.
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